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Product Information of Bio-samin
Bio-samin: Black Sesame Extracted Sesamin
Basic Info
Formal Name: 1,3,4,9,10,10aS-hexahydro-5,6-dihydroxy-
1,1-dimethyl-7-isopropyl-2H-9S,4aR-
(epoxymethano)phenanthren-12-one
Molecular Formula C20H26O4
Molecular Weight 330.4
Odor : Characteristic
Purity: No Less Than 90%
Stability: ¡Ý 3 years at -20℃
Supplied as: A crystalline solid
UV/Vis: ¦Ëmax: 285 nm
Laboratory Procedure
For long term storage, we suggest that sesamin be stored as supplied at -20℃. It will be stable for at least three years.
Sesamin is supplied as a crystalline solid. A stock solution may be made by dissolving the sesamin in an organic
solvent purged with an inert gas. Sesamin is soluble in organic solvents such as ethanol, DMSO, and dimethyl
formamide. The solubility of sesamin in these solvents is 0.5, 12, and 33 mg/ml, respectively. Sesamin will be stable
for at least six months in these solvents if stored at -20℃.
Sesamin is ***ringly soluble in aqueous buffers. Further dilutions of the stock solution into aqueous buffers or
isotonic saline should be made prior to performing biological experiments. For maximum solubility in aqueous
buffers, sesamin should first be dissolved in DMF and then diluted with the aqueous buffer of choice. Sesamin has a
solubility of 50 µg/ml in a 1:10 solution of DMF:PBS (pH 7.2) using this method. Store aqueous solutions of sesamin
on ice and use within 12 hours of preparation. Although the aqueous solutions of sesamin may be stable for more than
12 hours, we strongly recommend using a fresh preparation each day.
Sesamin is a non-competitive inhibitor of &©|8710;5-desaturase. It inhibits the conversion of dihomo-¦Ã-linolenic acid to
arachidonic acid with a Ki value of 155 µM in rat liver microsomes.1
Reference
1. Shimizu, S., Akimoto, K., Sugano, M., et al. Studies on desatura |
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